Impaired hepatic autophagy exacerbates hepatotoxin induced liver injury
Abstract Hepatotoxins activate the hepatic survival pathway, but it is unclear whether impaired survival pathways contribute to liver injury caused by hepatotoxins. We investigated the role of hepatic autophagy, a cellular survival pathway, in cholestatic liver injury driven by a hepatotoxin. Here w...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-02-01
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Series: | Cell Death Discovery |
Online Access: | https://doi.org/10.1038/s41420-023-01368-3 |