Endothelial-Derived Extracellular Vesicles Induce Cerebrovascular Dysfunction in Inflammation

Endothelial-Derived Extracellular Vesicles Induce Cerebrovascular Dysfunction in Inflammation

Blood–brain barrier (BBB) dysfunction is a key hallmark in the pathology of many neuroinflammatory disorders. Extracellular vesicles (EVs) are lipid membrane-enclosed carriers of molecular cargo that are involved in cell-to-cell communication. Circulating endothelial EVs are increased in the plasma...

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Bibliographic Details
Main Authors: David Roig-Carles, Eduard Willms, Ruud D. Fontijn, Sarai Martinez-Pacheco, Imre Mäger, Helga E. de Vries, Mark Hirst, Basil Sharrack, David K. Male, Cheryl A. Hawkes, Ignacio A. Romero
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Pharmaceutics
Subjects:
blood–brain barrier
cell-to-cell communication
exosomes
extracellular vesicles
neuroinflammation
Online Access:https://www.mdpi.com/1999-4923/13/9/1525

Internet

https://www.mdpi.com/1999-4923/13/9/1525

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