The Roles of Endo-Lysosomes in Unconventional Protein Secretion

The Roles of Endo-Lysosomes in Unconventional Protein Secretion

Protein secretion in general depends on signal sequence (also named leader sequence), a hydrophobic segment located at or close to the NH2-terminus of a secretory or membrane protein. This sequence guides the entry of nascent polypeptides into the lumen or membranes of the endoplasmic reticulum (ER)...

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Bibliographic Details
Main Authors: Juhyung Lee, Yihong Ye
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Cells
Subjects:
protein translocation
misfolding-associated protein secretion (MAPS)
unconventional protein secretion
endo-lysosome
intercellular transmission of proteins
protein quality control
neurodegenerative diseases
chaperone-mediated autophagy
Online Access:https://www.mdpi.com/2073-4409/7/11/198

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https://www.mdpi.com/2073-4409/7/11/198

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