Osteocytes as main responders to low-intensity pulsed ultrasound treatment during fracture healing

Abstract Ultrasound stimulation is a type of mechanical stress, and low-intensity pulsed ultrasound (LIPUS) devices have been used clinically to promote fracture healing. However, it remains unclear which skeletal cells, in particular osteocytes or osteoblasts, primarily respond to LIPUS stimulation...

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Bibliographic Details
Main Authors: Tatsuya Shimizu, Naomasa Fujita, Kiyomi Tsuji-Tamura, Yoshimasa Kitagawa, Toshiaki Fujisawa, Masato Tamura, Mari Sato
Format: Article
Language:English
Published: Nature Portfolio 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-89672-9