The angiotensin type 1 receptor antagonist valsartan attenuates pathological ventricular hypertrophy induced by hyperhomocysteinemia in rats

Introduction. Clinical and experimental studies have reported the role of homocysteine in ventricular hypertrophy. Activation of the reninangiotensin system mediated by angiotensin II type 1 (AT1) receptor has also been suggested to contribute to the pathogenesis of ventricular hypertrophy. There ar...

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Bibliographic Details
Main Authors: Salah Kassab, Taysir Garadah, Marwan Abu-Hijleh, Jamal Golbahar, Solomon Senok, Javed Wazir, Khalid Gumaa
Format: Article
Language:English
Published: SAGE Publications 2006-12-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.3317/jraas.2006.039