Effects of Hyperbaric Oxygen Intervention on the Degenerated Intervertebral Disc: From Molecular Mechanisms to Animal Models

Effects of Hyperbaric Oxygen Intervention on the Degenerated Intervertebral Disc: From Molecular Mechanisms to Animal Models

MicroRNA (miRNA) 107 expression is downregulated but Wnt3a protein and β-catenin are upregulated in degenerated intervertebral disc (IVD). We investigated mir-107/Wnt3a-β-catenin signaling in vitro and in vivo following hyperbaric oxygen (HBO) intervention. Our results showed 96 miRNAs were upregula...

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Bibliographic Details
Main Authors: Song-Shu Lin, Steve W. N. Ueng, Kowit-Yu Chong, Yi-Sheng Chan, Tsung-Ting Tsai, Li-Jen Yuan, Shih-Jung Liu, Chuen-Yung Yang, Hui-Yi Hsiao, Yi-Jen Hsueh, Chung-An Chen, Chi-Chien Niu
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Cells
Subjects:
microRNA
Wnt3a/β-catenin signaling
intervertebral disc
degeneration
hyperbaric oxygen
Online Access:https://www.mdpi.com/2073-4409/12/16/2111

Internet

https://www.mdpi.com/2073-4409/12/16/2111

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