Long term follow up of patients after allogeneic stem cell transplantation and transfusion of HSV-Tk transduced T-cells.

Allogeneic stem cell transplantation (allo-HSCT) is one of the curative treatments for hematologic malignancies, but is hampered by severe complications, such as acute or chronic graft-versus-host-disease (aGvHD; cGvHD) and infections. CD34-selcetion of stem cells reduces the risk of aGvHD, but also...

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Main Authors: Eva Maria Weissinger, Sylvia eBorchers, Anna eSilvani, Elena eProvasi, Marina eRadrizzani, Irene Katarina Beckmann, Claudia eBenati, Joerg eSchmidtke, Wolfgang eKuehnau, Patrick eSchweier, Susanne eLuther, Ivonne eFernadez-Munoz, Gernot eBeutel, Fabio eCiceri, Chiara eBonini, Arnold eGanser, Bernd eHertenstein, Michael eStadler
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-04-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00076/full