Nicotinamide phosphoribosyltransferase may be involved in age-related brain diseases.

Nicotinamide phosphoribosyltransferase (NAMPT) is a key enzyme for nicotinamide adenine dinucleotide (NAD) biosynthesis, and can be found either intracellularly (iNAMPT) or extracellularly (eNAMPT). Studies have shown that both iNAMPT and eNAMPT are implicated in aging and age-related diseases/disor...

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Bibliographic Details
Main Authors: Li-Ying Liu, Feng Wang, Xia-Yan Zhang, Peng Huang, Yun-Bi Lu, Er-Qing Wei, Wei-Ping Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3469563?pdf=render