Determination of a clinically effective evobrutinib dose: Exposure–response analyses of a phase II relapsing multiple sclerosis study

Abstract The pharmacometric analysis of the double‐blind, randomized, phase II study (NCT02975349) investigating the safety and efficacy of evobrutinib, explored exposure–response relationships and suitable dosing regimens of evobrutinib for relapsing multiple sclerosis. Population pharmacokinetic (...

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Bibliographic Details
Main Authors: Orestis Papasouliotis, David Mitchell, Pascal Girard, Fernando Dangond, Martin Dyroff
Format: Article
Language:English
Published: Wiley 2022-12-01
Series:Clinical and Translational Science
Online Access:https://doi.org/10.1111/cts.13407