Antigenic Characterization of New Lineage II Insect-Specific Flaviviruses in Australian Mosquitoes and Identification of Host Restriction Factors

Antigenic Characterization of New Lineage II Insect-Specific Flaviviruses in Australian Mosquitoes and Identification of Host Restriction Factors

ABSTRACT We describe two new insect-specific flaviviruses (ISFs) isolated from mosquitoes in Australia, Binjari virus (BinJV) and Hidden Valley virus (HVV), that grow efficiently in mosquito cells but fail to replicate in a range of vertebrate cell lines. Phylogenetic analysis revealed that BinJV an...

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Bibliographic Details
Main Authors: Jessica J. Harrison, Jody Hobson-Peters, Agathe M. G. Colmant, Joanna Koh, Natalee D. Newton, David Warrilow, Helle Bielefeldt-Ohmann, Thisun B. H. Piyasena, Caitlin A. O’Brien, Laura J. Vet, Devina Paramitha, James R. Potter, Steven S. Davis, Cheryl A. Johansen, Yin Xiang Setoh, Alexander A. Khromykh, Roy A. Hall
Format: Article
Language:English
Published: American Society for Microbiology 2020-06-01
Series:mSphere
Subjects:
Aedeomyia catasticta
Aedes normanensis
Binjari virus
Hidden Valley virus
chimeric virus
circular polymerase extension reaction
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00095-20

Internet

https://journals.asm.org/doi/10.1128/mSphere.00095-20

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