Who’s afraid of the X? Incorporating the X and Y chromosomes into the analysis of DNA methylation array data

Abstract Background Many human disease phenotypes manifest differently by sex, making the development of methods for incorporating X and Y-chromosome data into analyses vital. Unfortunately, X and Y chromosome data are frequently excluded from large-scale analyses of the human genome and epigenome d...

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Bibliographic Details
Main Authors: Amy M. Inkster, Martin T. Wong, Allison M. Matthews, Carolyn J. Brown, Wendy P. Robinson
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Epigenetics & Chromatin
Subjects:
Online Access:https://doi.org/10.1186/s13072-022-00477-0