Conventional and Unconventional Mechanisms by which Exocytosis Proteins Oversee β-cell Function and Protection

Conventional and Unconventional Mechanisms by which Exocytosis Proteins Oversee β-cell Function and Protection

Type 2 diabetes (T2D) is one of the prominent causes of morbidity and mortality in the United States and beyond, reaching global pandemic proportions. One hallmark of T2D is dysfunctional glucose-stimulated insulin secretion from the pancreatic β-cell. Insulin is secreted via the recruitment of insu...

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Bibliographic Details
Main Authors: Diti Chatterjee Bhowmick, Miwon Ahn, Eunjin Oh, Rajakrishnan Veluthakal, Debbie C. Thurmond
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
insulin secretion
exocytosis
STX4
DOC2b
β-cell mass
β-cell function
Online Access:https://www.mdpi.com/1422-0067/22/4/1833

Internet

https://www.mdpi.com/1422-0067/22/4/1833

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