Design, synthesis, biological evaluation and in silico studies of novel 1,2,3-triazole linked benzoxazine-2,4-dione conjugates as potent antimicrobial, antioxidant and anti-inflammatory agents

Design, synthesis, biological evaluation and in silico studies of novel 1,2,3-triazole linked benzoxazine-2,4-dione conjugates as potent antimicrobial, antioxidant and anti-inflammatory agents

In an attempt to rationalize the search for new potential anti-inflammatory and anti-infection agents, a new series of 1,4-and 1,5-disubstituted 1,2,3-triazoles linked benzoxazine conjugates have been synthesized via “Click Chemistry” reaction, were designed, synthesized and characterized by means o...

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Bibliographic Details
Main Authors: Manel Ben Hammouda, Iqrar Ahmad, Assia Hamdi, Amal Dbeibia, Harun Patel, Nouha Bouali, Walid Sabri Hamadou, Karim Hosni, Siwar Ghannay, Fahad Alminderej, Emira Noumi, Mejdi Snoussi, Kaïss Aouadi, Adel Kadri
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Arabian Journal of Chemistry
Subjects:
1,4- and 1,5-disubstituted 1,2,3-triazoles
Click chemistry
Antimicrobial
Antioxidant
Ant-inflammatory
In silico studies
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535222005421

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http://www.sciencedirect.com/science/article/pii/S1878535222005421

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