A positive feedback loop between tryptophan hydroxylase 1 and β-Catenin/ZBP-89 signaling promotes prostate cancer progression

A positive feedback loop between tryptophan hydroxylase 1 and β-Catenin/ZBP-89 signaling promotes prostate cancer progression

Alterations in tryptophan (Trp) metabolism facilitate the continuous modulation of tumor progression, including tumor growth, distant metastasis, and chemoresistance development. Although there is a high correlation between Trp metabolism and tumor progression, it is unknown whether and how Trp meta...

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Bibliographic Details
Main Authors: Chengguo Ge, Jiusong Yan, Xiaoyu Yuan, Guangyong Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Oncology
Subjects:
tryptophan hydroxylase 1
5-hydroxytryptamine
beta-catenin
ZBP-89
prostate cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.923307/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.923307/full

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