Influence of thymidylate synthase expression on survival in patients with colorectal cancer

Influence of thymidylate synthase expression on survival in patients with colorectal cancer

Background: Thymidylate synthase (TS) plays a critical role in nucleotide metabolism and is an important target for 5-fluorouracil (5-FU), the standard chemotherapeutic drug for treatment of colorectal cancer (CRC). Aims and Methods: The present study aimed to evaluate TS variable number tandem repe...

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Bibliographic Details
Main Authors: Kinjal K Gajjar, Toral P Kobawala, Trupti I Trivedi, Hemangini H Vora, Nandita R Ghosh
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:International Journal of Advanced Medical and Health Research
Subjects:
5-fluorouracil
colorectal cancer
protein expression
thymidylate synthase
variable number tandem repeat polymorphism
Online Access:http://www.ijamhrjournal.org/article.asp?issn=2349-4220;year=2017;volume=4;issue=2;spage=61;epage=68;aulast=Gajjar

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http://www.ijamhrjournal.org/article.asp?issn=2349-4220;year=2017;volume=4;issue=2;spage=61;epage=68;aulast=Gajjar

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