Development of Anti-Virulence Therapeutics against Mono-ADP-Ribosyltransferase Toxins

Mono-ADP-ribosyltransferase toxins are often key virulence factors produced by pathogenic bacteria as tools to compromise the target host cell. These toxins are enzymes that use host cellular NAD<sup>+</sup> as the substrate to modify a critical macromolecule target in the host cell mach...

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Bibliographic Details
Main Authors: Miguel R. Lugo, Allan R. Merrill
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/13/1/16