Lyssavirus matrix protein inhibits NLRP3 inflammasome assembly by binding to NLRP3

Summary: Lyssavirus is a kind of neurotropic pathogen that needs to evade peripheral host immunity to enter the central nervous system to accomplish infection. NLRP3 inflammasome activation is essential for the host to defend against pathogen invasion. This study demonstrates that the matrix protein...

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Bibliographic Details
Main Authors: Baokun Sui, Jianqing Zhao, Jinxiao Wang, Jiaxin Zheng, Rui Zhou, Di Wu, Zonghui Zeng, Yueming Yuan, Zhenfang Fu, Ling Zhao, Ming Zhou
Format: Article
Language:English
Published: Elsevier 2024-07-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724008076