MPL W515L/K Mutations in Chronic Myeloproliferative Neoplasms

MPL W515L/K Mutations in Chronic Myeloproliferative Neoplasms

OBJECTIVE: The MPL gene encodes the thrombopoietin receptor. Recently MPL mutations (MPL W515L or MPL W515K) were described in patients with essential thrombocythemia (ET) and primary (idiopathic) myelofibrosis (PMF). The prevalence and the clinical importance of these mutations are not clear. In th...

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Bibliographic Details
Main Authors: Timur Selçuk Akpınar, Veysel Sabri Hançer, Meliha Nalçacı, Reyhan Diz- Küçükkaya
Format: Article
Language:English
Published: Galenos Publishing House 2013-03-01
Series:Turkish Journal of Hematology
Subjects:
mpl w515l/k mutations
jak-2 v617f mutation
myeloproliferative neoplasms
essential thrombocythemia
primary myelofibrosis
Online Access:https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tjh&un=TJH-65807

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https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tjh&un=TJH-65807

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