Targeting virulence regulation to disarm Acinetobacter baumannii pathogenesis

Targeting virulence regulation to disarm Acinetobacter baumannii pathogenesis

The development of anti-virulence drug therapy against Acinetobacter baumannii infections would provide an alternative to traditional antibacterial therapy that are increasingly failing. Here, we demonstrate that the OmpR transcriptional regulator plays a pivotal role in the pathogenesis of diverse...

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Bibliographic Details
Main Authors: Vincent Trebosc, Valentina Lucchini, Mohit Narwal, Basil Wicki, Sarah Gartenmann, Birgit Schellhorn, Julian Schill, Marilyne Bourotte, Daniel Frey, Jürgen Grünberg, Andrej Trauner, Livia Ferrari, Antonio Felici, Olivia L. Champion, Marc Gitzinger, Sergio Lociuro, Richard A. Kammerer, Christian Kemmer, Michel Pieren
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Virulence
Subjects:
OmpR
A. baumannii
virulence
drug discovery
Online Access:https://www.tandfonline.com/doi/10.1080/21505594.2022.2135273

Internet

https://www.tandfonline.com/doi/10.1080/21505594.2022.2135273

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