Data-driven multiscale modeling reveals the role of metabolic coupling for the spatio-temporal growth dynamics of yeast colonies

Data-driven multiscale modeling reveals the role of metabolic coupling for the spatio-temporal growth dynamics of yeast colonies

Abstract Background Multicellular entities like mammalian tissues or microbial biofilms typically exhibit complex spatial arrangements that are adapted to their specific functions or environments. These structures result from intercellular signaling as well as from the interaction with the environme...

Full description

Bibliographic Details
Main Authors: Jukka Intosalmi, Adrian C. Scott, Michelle Hays, Nicholas Flann, Olli Yli-Harja, Harri Lähdesmäki, Aimée M. Dudley, Alexander Skupin
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Molecular and Cell Biology
Subjects:
Multicellular systems
Multiscale modeling
Yeast colony
Metabolic coupling
Diauxic shift
Markov chain Monte Carlo
Online Access:https://doi.org/10.1186/s12860-019-0234-z

Internet

https://doi.org/10.1186/s12860-019-0234-z

Similar Items