Comprehensive Characterization of CK1δ-Mediated Tau Phosphorylation in Alzheimer’s Disease

Comprehensive Characterization of CK1δ-Mediated Tau Phosphorylation in Alzheimer’s Disease

A main pathological event in Alzheimer’s disease is the generation of neurofibrillary tangles originating from hyperphosphorylated and subsequently aggregated tau proteins. Previous reports demonstrated the critical involvement of members of the protein kinase family CK1 in the pathogenesis of Alzhe...

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Bibliographic Details
Main Authors: Aileen Roth, Annabelle Sander, Marleen Silke Oswald, Fabian Gärtner, Uwe Knippschild, Joachim Bischof
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Molecular Biosciences
Subjects:
Alzheimer’s disease
AD
casein kinase 1δ
CK1δ
tau phosphorylation
tau aggregation
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.872171/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2022.872171/full

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