Distinct subsets of multi-lymphoid progenitors support ontogeny-related changes in human lymphopoiesis

Distinct subsets of multi-lymphoid progenitors support ontogeny-related changes in human lymphopoiesis

Summary: Changes in lymphocyte production patterns occurring across human ontogeny remain poorly defined. In this study, we demonstrate that human lymphopoiesis is supported by three waves of embryonic, fetal, and postnatal multi-lymphoid progenitors (MLPs) differing in CD7 and CD10 expression and t...

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Bibliographic Details
Main Authors: Seydou Keita, Samuel Diop, Shalva Lekiashvili, Emna Chabaane, Elisabeth Nelson, Marion Strullu, Chloé Arfeuille, Fabien Guimiot, Thomas Domet, Sophie Duchez, Bertrand Evrard, Thomas Darde, Jerome Larghero, Els Verhoeyen, Ana Cumano, Elizabeth A. Macintyre, Zeinab Kasraian, François Jouen, Michele Goodhardt, David Garrick, Frederic Chalmel, Kutaiba Alhaj Hussen, Bruno Canque
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Cell Reports
Subjects:
CP: Developmental biology
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723006290

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http://www.sciencedirect.com/science/article/pii/S2211124723006290

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