Development of Bifunctional Chiral Thioureas and Thiosquaramides in the Synthesis of Betti Bases

Bifunctional thioureas and, for the first time, bifunctional thiosquaramides as organocatalysts were used in the asymmetric Betti reaction involving 1-, 2-naphthols and hydroxyquinoline with <i>N</i>-tosylimine and ketimine. The described methodology affords direct access to chiral amino...

Full description

Bibliographic Details
Main Authors: Martyna Malinowska, Anna Zawisza
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/28/23/7835