Seminoma and dysgerminoma: evidence for alignment of clinical trials and de-escalation of systemic chemotherapy

Seminoma and dysgerminoma: evidence for alignment of clinical trials and de-escalation of systemic chemotherapy

Malignant germ cell tumours are a group of rare cancers whose incidence peaks in late adolescence and early adulthood. Dysgerminomas of the ovary and seminomas of the testis are analogous diseases, but seminomas have a 10-fold higher incidence. The two tumours are morphologically identical and are o...

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Bibliographic Details
Main Authors: Georgina E. Wood, Christopher P. Bunting, Mesel Veli, Rupali Arora, Daniel M. Berney, Constantine Alifrangis, Nicola D. MacDonald, Rowan E. Miller, Jonathan Shamash, Sara Stoneham, Michelle Lockley
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Oncology
Subjects:
systemic chemotherapy
carboplatin
germ cell tumours
seminoma
dysgerminoma
de-escalating chemotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1271647/full

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https://www.frontiersin.org/articles/10.3389/fonc.2023.1271647/full

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