Analysis of KLF4 regulated genes in cancer cells reveals a role of DNA methylation in promoter- enhancer interactions

Recent studies have revealed an unexpected role of DNA methylation at promoter regions in transcription activation. However, whether DNA methylation at enhancer regions activates gene expression and influences cellular functions remains to be determined. In this study, by employing the transcription...

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Bibliographic Details
Main Authors: Olutobi Oyinlade, Shuang Wei, Kai Kammers, Sheng Liu, Shuyan Wang, Ding Ma, Zhi-yong Huang, Jiang Qian, Heng Zhu, Jun Wan, Shuli Xia
Format: Article
Language:English
Published: Taylor & Francis Group 2018-07-01
Series:Epigenetics
Subjects:
Online Access:http://dx.doi.org/10.1080/15592294.2018.1504592