GSTP alleviates acute lung injury by S-glutathionylation of KEAP1 and subsequent activation of NRF2 pathway

GSTP alleviates acute lung injury by S-glutathionylation of KEAP1 and subsequent activation of NRF2 pathway

Oxidative stress plays an important role in the pathogenesis of acute lung injury (ALI). As a typical post-translational modification triggered by oxidative stress, protein S-glutathionylation (PSSG) is regulated by redox signaling pathways and plays diverse roles in oxidative stress conditions. In...

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Bibliographic Details
Main Authors: Xiaolin Sun, Chaorui Guo, Chunyan Huang, Ning Lv, Huili Chen, Haoyan Huang, Yulin Zhao, Shanliang Sun, Di Zhao, Jingwei Tian, Xijing Chen, Yongjie Zhang
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Redox Biology
Subjects:
GSTP
S-glutathionylation
Acute lung injury
Oxidative stress
KEAP1
NRF2
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231724000922

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http://www.sciencedirect.com/science/article/pii/S2213231724000922

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