Microproteins: Overlooked regulators of physiology and disease

Summary: Ongoing efforts to generate a complete and accurate annotation of the genome have revealed a significant blind spot for small proteins (<100 amino acids) originating from short open reading frames (sORFs). The recent discovery of numerous sORF-encoded proteins, termed microproteins, that...

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Bibliographic Details
Main Authors: Keira R. Hassel, Omar Brito-Estrada, Catherine A. Makarewich
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223008581