Translational impacts of enzymes that modify ribosomal RNA around the peptidyl transferase centre

Large ribosomal RNAs (rRNAs) are modified heavily post-transcriptionally in functionally important regions but, paradoxically, individual knockouts (KOs) of the modification enzymes have minimal impact on Escherichia coli growth. Furthermore, we recently constructed a strain with combined KOs of fiv...

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Bibliographic Details
Main Authors: Letian Bao, Josefine Liljeruhm, Rubén Crespo Blanco, Gerrit Brandis, Jaanus Remme, Anthony C. Forster
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:RNA Biology
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/15476286.2024.2368305