Multiple clinical characteristics separate MED12-mutation-positive and -negative uterine leiomyomas
Abstract Up to 86% of uterine leiomyomas harbour somatic mutations in mediator complex subunit 12 (MED12). These mutations have been associated with conventional histology, smaller tumour size, and larger number of tumours within the uterus. Prior studies, with limited sample sizes, have failed to d...
المؤلفون الرئيسيون: | , , , , , , , , , , , |
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التنسيق: | مقال |
اللغة: | English |
منشور في: |
Nature Portfolio
2017-04-01
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سلاسل: | Scientific Reports |
الوصول للمادة أونلاين: | https://doi.org/10.1038/s41598-017-01199-0 |