Targeted delivery of autoantigen to dendritic cells prevents development of spontaneous uveitis

Restoration of immunological tolerance to self antigens has been a major drive in understanding the mechanisms of, and developing new treatments for, autoimmune and autoinflammatory disease. Sessile dendritic cells (DC) are considered the main instruments underpinning immunological tolerance particu...

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Bibliographic Details
Main Authors: Izabela P. Klaska, Tian Yu, Rosie Fordyce, Koju Kamoi, Richard J. Cornall, Cristina Martin-Granados, Lucia Kuffova, John V. Forrester
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1227633/full