Individualized therapy: Role of thiopurine S-methyltransferase protein and genetic variants
Thiopurine S-methyltransferase (TPMT: EC 2.1.1.67) is an enzyme that metabolizes immunosuppressive thiopurine medications, used in the treatment of autoimmune diseases, cancer and in transplantation medicine. In some individuals, TPMT enzyme activity is significantly increased or decreased compared...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Society of Medical Biochemists of Serbia, Belgrade
2010-01-01
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Series: | Journal of Medical Biochemistry |
Subjects: | |
Online Access: | https://scindeks-clanci.ceon.rs/data/pdf/1452-8258/2010/1452-82581003150P.pdf |