Validation and Clinical Application of a New Liquid Chromatography Coupled to Mass Spectrometry (HPLC-MS) Method for Dalbavancin Quantification in Human Plasma

Validation and Clinical Application of a New Liquid Chromatography Coupled to Mass Spectrometry (HPLC-MS) Method for Dalbavancin Quantification in Human Plasma

Dalbavancin (DBV) is an intravenous long-acting second-generation glycolipopeptide antibiotic with high efficacy and excellent tolerability, approved for use in the treatment of Gram-positive skin and skin structure infections (ABSSSI). Nevertheless, little is known about its pharmacokinetic/pharmac...

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Bibliographic Details
Main Authors: Valeria Avataneo, Miriam Antonucci, Elisa Delia De Vivo, Antonio Briozzo, Jessica Cusato, Francesca Bermond, Corrado Vitale, Francesco Vitale, Alessandra Manca, Alice Palermiti, Giovanni Di Perri, Francesco Giuseppe De Rosa, Amedeo De Nicolò, Antonio D’Avolio
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Separations
Subjects:
dalbavancin
therapeutic drug monitoring
long-acting therapy
glycopeptides
MRSA
skin infections
Online Access:https://www.mdpi.com/2297-8739/8/10/189

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https://www.mdpi.com/2297-8739/8/10/189

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