Novel data analysis method for multicolour flow cytometry links variability of multiple markers on single cells to a clinical phenotype

Abstract Multicolour Flow Cytometry (MFC) produces multidimensional analytical data on the quantitative expression of multiple markers on single cells. This data contains invaluable biomedical information on (1) the marker expressions per cell, (2) the variation in such expression across cells, (3)...

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Bibliographic Details
Main Authors: Gerjen H. Tinnevelt, Marietta Kokla, Bart Hilvering, Selma van Staveren, Rita Folcarelli, Luzheng Xue, Andries C. Bloem, Leo Koenderman, Lutgarde M. C. Buydens, Jeroen J. Jansen
Format: Article
Language:English
Published: Nature Portfolio 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-05714-1