Effects of Rutin and Hesperidin and Their Al(III) and Cu(II) Complexes on in Vitro Plasma Coagulation Assays

Two flavonoids, rutin and hesperidin, were investigated in vitro for anticoagulant activity through coagulation tests: activated partial thromboplastin time (aPTT), prothrombin time (PT) and thrombin time (TT). Only an ethanolic solution of rutin at the concentration of 830 µM prolonged aPTT, while...

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Bibliographic Details
Main Authors: Vesna Kuntić, Zorica Vujić, Ivana Filipović
Format: Article
Language:English
Published: MDPI AG 2011-02-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/16/2/1378/