Prediction of small molecule drug-miRNA associations based on GNNs and CNNs

Prediction of small molecule drug-miRNA associations based on GNNs and CNNs

MicroRNAs (miRNAs) play a crucial role in various biological processes and human diseases, and are considered as therapeutic targets for small molecules (SMs). Due to the time-consuming and expensive biological experiments required to validate SM-miRNA associations, there is an urgent need to develo...

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Bibliographic Details
Main Authors: Zheyu Niu, Xin Gao, Zhaozhi Xia, Shuchao Zhao, Hongrui Sun, Heng Wang, Meng Liu, Xiaohan Kong, Chaoqun Ma, Huaqiang Zhu, Hengjun Gao, Qinggong Liu, Faji Yang, Xie Song, Jun Lu, Xu Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Genetics
Subjects:
small molecule drug
miRNAs
graph neural networks
convolutional neural networks
CNN
liver cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1201934/full

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https://www.frontiersin.org/articles/10.3389/fgene.2023.1201934/full

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