Nanoscale coordination polymer Fe-DMY downregulating Poldip2-Nox4-H2O2 pathway and alleviating diabetic retinopathy

Nanoscale coordination polymer Fe-DMY downregulating Poldip2-Nox4-H2O2 pathway and alleviating diabetic retinopathy

Diabetic retinopathy (DR) is a prevalent microvascular complication of diabetes and the leading cause of blindness and severe visual impairment in adults. The high levels of glucose trigger multiple intracellular oxidative stress pathways, such as POLDIP2, resulting in excessive reactive oxygen spec...

Full description

Bibliographic Details
Main Authors: Si-Yu Gui, Xin-Chen Wang, Zhi-Hao Huang, Mei-Mei Li, Jia-Hao Wang, Si-Yin Gui, Gan-Hua Zhang, Yao Lu, Li-Ming Tao, Hai-Sheng Qian, Zheng-Xuan Jiang
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Journal of Pharmaceutical Analysis
Subjects:
Nano-coordinated polymer particles
Bioactive molecules delivery
Antioxidant
Anti-angiogenesis
Diabetic retinopathy treatment
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177923000904

Internet

http://www.sciencedirect.com/science/article/pii/S2095177923000904

Similar Items