Core Fucosylation Regulates the Function of Pre-BCR, BCR and IgG in Humoral Immunity

Most of the membrane molecules involved in immune response are glycosylated. N-glycans linked to asparagine (Asn) of immune molecules contribute to the protein conformation, surface expression, stability, and antigenicity. Core fucosylation catalyzed by core fucosyltransferase (FUT8) is the most com...

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Bibliographic Details
Main Authors: Yuhan Sun, Xueying Li, Tiantong Wang, Wenzhe Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.844427/full