First report of clinical responses to immunotherapy in 3 relapsing cases of chordoma after failure of standard therapies

First report of clinical responses to immunotherapy in 3 relapsing cases of chordoma after failure of standard therapies

Chordoma is a rare tumor of notochordal origin, currently principally treated by surgery and/or irradiation. Here, we describe the clinical outcome of 3 consecutive patients with metastatic and locally advanced chordoma, treated with different immunotherapeutic approaches. All patients presented fas...

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Bibliographic Details
Main Authors: Denis Migliorini, Nicolas Mach, Diego Aguiar, Rémi Vernet, Basile Nicolas Landis, Minerva Becker, Thomas McKee, Valérie Dutoit, Pierre-Yves Dietrich
Format: Article
Language:English
Published: Taylor & Francis Group 2017-08-01
Series:OncoImmunology
Subjects:
chordoma
brachyury
immunotherapy
immune checkpoint inhibitors
melanoma antigens
neoantigen
tumor vaccine
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1338235

Internet

http://dx.doi.org/10.1080/2162402X.2017.1338235

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