Modular co-culture engineering of Yarrowia lipolytica for amorphadiene biosynthesis
Abstract Amorphadiene is the precursor to synthesize the antimalarial drug artemisinin. The production of amorphadiene and artemisinin from metabolically engineered microbes may provide an alternate to plant secondary metabolite extraction. Microbial consortia can offer division of labor, and microb...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-12-01
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Series: | Microbial Cell Factories |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12934-022-02010-0 |