Extracellular vesicles derived from nasopharyngeal carcinoma induce the emergence of mature regulatory dendritic cells using a galectin‐9 dependent mechanism

Extracellular vesicles derived from nasopharyngeal carcinoma induce the emergence of mature regulatory dendritic cells using a galectin‐9 dependent mechanism

Abstract Nasopharyngeal carcinoma‐derived small extracellular vesicles (NPCSEVs) have an immunosuppressive impact on the tumour microenvironment. In this study, we investigated their influence on the generation of tolerogenic dendritic cells and the potential involvement of the galectin‐9 (Gal9) the...

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Bibliographic Details
Main Authors: Anthony Lefebvre, Camille Trioën, Sarah Renaud, William Laine, Benjamin Hennart, Clément Bouchez, Bertrand Leroux, Delphine Allorge, Jérôme Kluza, Elisabeth Werkmeister, Guillaume Paul Grolez, Nadira Delhem, Olivier Moralès
Format: Article
Language:English
Published: Wiley 2023-12-01
Series:Journal of Extracellular Vesicles
Subjects:
extracellular vesicles
galectin‐9
IDO
IL‐4
IL4I1
mature regulatory dendritic cells
Online Access:https://doi.org/10.1002/jev2.12390

Internet

https://doi.org/10.1002/jev2.12390

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