Mitochondria as biological targets for stem cell and organismal senescence

Organismal aging is impacted by the deterioration of tissue turnover mechanisms due, in part, to the decline in stem cell function. This decline can be related to mitochondrial dysfunction and underlying energetic defects that, in concert, help drive biological aging. Thus, mitochondria have been de...

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Bibliographic Details
Main Authors: Ana Branco, Inês Moniz, João Ramalho-Santos
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:European Journal of Cell Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0171933523000043