Antispasmodic Effect of Asperidine B, a Pyrrolidine Derivative, through Inhibition of L-Type Ca<sup>2+</sup> Channel in Rat Ileal Smooth Muscle

Antispasmodic Effect of Asperidine B, a Pyrrolidine Derivative, through Inhibition of L-Type Ca<sup>2+</sup> Channel in Rat Ileal Smooth Muscle

Antispasmodic agents are used for modulating gastrointestinal motility. Several compounds isolated from terrestrial plants have antispasmodic properties. This study aimed to explore the inhibitory effect of the pyrrolidine derivative, asperidine B, isolated from the soil-derived fungus <i>Aspe...

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Bibliographic Details
Main Authors: Acharaporn Duangjai, Vatcharin Rukachaisirikul, Yaowapa Sukpondma, Chutima Srimaroeng, Chatchai Muanprasat
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Molecules
Subjects:
pyrrolidine derivative
relaxation
smooth muscle
ileum
calcium channel
Online Access:https://www.mdpi.com/1420-3049/26/18/5492

Internet

https://www.mdpi.com/1420-3049/26/18/5492

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