Unexpected Enhancement of Antimicrobial Polymer Activity against <i>Staphylococcus aureus</i> in the Presence of Fetal Bovine Serum

Cationic and amphiphilic polymers are known to exert broad-spectrum antibacterial activity by a putative mechanism of membrane disruption. Typically, nonspecific binding to hydrophobic components of the complex biological milieu, such as globular proteins, is considered a deterrent to the successful...

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Bibliographic Details
Main Authors: Iva Sovadinová, Kenichi Kuroda, Edmund F. Palermo
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/26/15/4512