Characterizing mutational heterogeneity in a glioblastoma patient with double recurrence.

Characterizing mutational heterogeneity in a glioblastoma patient with double recurrence.

Human cancers are driven by the acquisition of somatic mutations. Separating the driving mutations from those that are random consequences of general genomic instability remains a challenge. New sequencing technology makes it possible to detect mutations that are present in only a minority of cells...

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Bibliographic Details
Main Authors: Gabrielle C Nickel, Jill Barnholtz-Sloan, Meetha P Gould, Sarah McMahon, Andrea Cohen, Mark D Adams, Kishore Guda, Mark Cohen, Andrew E Sloan, Thomas LaFramboise
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3335059?pdf=render

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http://europepmc.org/articles/PMC3335059?pdf=render

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