Impairing proliferation of glioblastoma multiforme with CD44+ selective conjugated polymer nanoparticles

Impairing proliferation of glioblastoma multiforme with CD44+ selective conjugated polymer nanoparticles

Abstract Glioblastoma is one of the most aggressive types of cancer with success of therapy being hampered by the existence of treatment resistant populations of stem-like Tumour Initiating Cells (TICs) and poor blood–brain barrier drug penetration. Therapies capable of effectively targeting the TIC...

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Bibliographic Details
Main Authors: Dorota Lubanska, Sami Alrashed, Gage T. Mason, Fatima Nadeem, Angela Awada, Mitchell DiPasquale, Alexandra Sorge, Aleena Malik, Monika Kojic, Mohamed A. R. Soliman, Ana C. deCarvalho, Abdalla Shamisa, Swati Kulkarni, Drew Marquardt, Lisa A. Porter, Simon Rondeau-Gagné
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-15244-0

Internet

https://doi.org/10.1038/s41598-022-15244-0

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