Simultaneous Determination of Purpurin, Munjistin and Mollugin in Rat Plasma by Ultra High Performance Liquid Chromatography-Tandem Mass Spectrometry: Application to a Pharmacokinetic Study after Oral Administration of Rubia cordifolia L. Extract

Simultaneous Determination of Purpurin, Munjistin and Mollugin in Rat Plasma by Ultra High Performance Liquid Chromatography-Tandem Mass Spectrometry: Application to a Pharmacokinetic Study after Oral Administration of Rubia cordifolia L. Extract

A specific, simple, sensitive Ultra High Performance Liquid Chromatography-tandem Mass Spectrometry (UHPLC-MS/MS) method has been developed and validated for the simultaneous determination and pharmacokinetic study of purpurin, munjistin, and mollugin in rat plasma. Chromatographic separation was ca...

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Bibliographic Details
Main Authors: Mingjie Gao, Jing Yang, Zhibin Wang, Bingyou Yang, Haixue Kuang, Lu Liu, Liqian Wang, Chunjuan Yang
Format: Article
Language:English
Published: MDPI AG 2016-06-01
Series:Molecules
Subjects:
UHPLC-MS/MS
Rubia cordifolia L.
purpurin
munjistin
mollugin
pharmacokinetics
Online Access:http://www.mdpi.com/1420-3049/21/6/717

Internet

http://www.mdpi.com/1420-3049/21/6/717

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