Preclinical evaluation of PAC1 targeting with radiolabeled Maxadilan

Abstract There is an ongoing search for new tracers to optimize imaging of beta cell-derived tumors (insulinomas). The PAC1 receptor, expressed by insulinomas, can be used for targeting of these tumors. Here, we investigated whether radiolabeled maxadilan could be used for insulinoma imaging. Maxadi...

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Bibliographic Details
Main Authors: Lieke Joosten, Maarten Brom, Martin K. H. Schäfer, Otto C. Boerman, Eberhard Weihe, Martin Gotthardt
Format: Article
Language:English
Published: Nature Portfolio 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-01852-8