Cooperative RNA degradation stabilizes intermediate epithelial-mesenchymal states and supports a phenotypic continuum
Summary: Multiple intermediate epithelial-mesenchymal transition (EMT) states reflecting hybrid epithelial and mesenchymal phenotypes were observed in physiological and pathological conditions. Previous theoretical models explaining multiple EMT states rely on regulatory loops involving transcriptio...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-10-01
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Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004222014961 |