Insights into receptor structure and dynamics at the surface of living cells

It is challenging to approach protein structures in living cells. Here the authors investigate Interleukin-4 receptor alpha, which has a noncanonical amino acid incorporated at different locations, and see that evaluating click efficiency with calibrated imaging gives information on structure-relate...

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Bibliographic Details
Main Authors: Frederik Steiert, Peter Schultz, Siegfried Höfinger, Thomas D. Müller, Petra Schwille, Thomas Weidemann
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-37284-4