Automatic Reconstruction of Mitochondria and Endoplasmic Reticulum in Electron Microscopy Volumes by Deep Learning

Together, mitochondria and the endoplasmic reticulum (ER) occupy more than 20% of a cell's volume, and morphological abnormality may lead to cellular function disorders. With the rapid development of large-scale electron microscopy (EM), manual contouring and three-dimensional (3D) reconstructi...

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Bibliographic Details
Main Authors: Jing Liu, Linlin Li, Yang Yang, Bei Hong, Xi Chen, Qiwei Xie, Hua Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.00599/full